Gormsen, L. C., Svart, M., Thomsen, H. H., Søndergaard, E., Vendelbo, M., Christensen, N. L., Tolbod, L. P., Harms, H. J.
, Nielsen, R., Wiggers, H., Jessen, N., Hansen, J., Bøtker, H. E. & Møller, N. (2017).
Ketone Body Infusion With 3-Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study.
Journal of the American Heart Association,
6(3), 1-11. Article e005066.
https://doi.org/10.1161/JAHA.116.005066
Jensen, D., Kierulf-Lassen, C., Kristensen, M. L. V., Nørregaard, R., Weyer, K., Nielsen, R., Christensen, E. I. & Birn, H. (2017).
Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats.
PLoS One,
12(6), Article e0178796.
https://doi.org/10.1371/journal.pone.0178796
Svart, M., Rittig, N., Opstrup, U. K., Voss, T. S., Møller, N. & Jessen, N. (2017).
Metabolic effects of insulin in a human model of ketoacidosis combining exposure to lipopolysaccharide and insulin deficiency: a randomised, controlled, crossover study in individuals with type 1 diabetes.
Diabetologia,
60(7), 1197-1206.
https://doi.org/10.1007/s00125-017-4271-x
Kristensen, M. M., Davidsen, P. K., Vigelsø Hansen, A., Hansen, CN., Jensen, L. J.
, Jessen, N., Bruun, J. M., Dela, F. & Helge, J. W. (2017).
miRNAs in human subcutaneous adipose tissue: Effects of weight loss induced by hypocaloric diet and exercise.
Obesity,
25(3), 572-580.
https://doi.org/10.1002/oby.21765
Kjær, T. N., Ornstrup, M. J., Poulsen, M. M., Stødkilde-Jørgensen, H., Jessen, N., Jørgensen, J. O. L., Richelsen, B. & Pedersen, S. B. (2017).
No beneficial effects of resveratrol on the metabolic syndrome: A randomized placebo-controlled clinical trial.
Journal of Clinical Endocrinology and Metabolism,
102(5), 1642-1651.
https://doi.org/10.1210/jc.2016-2160
Laursen, M.
, Thinggaard, L. B., Kehler, J., Christoffersen, C. T., Bundgaard, C.
, Mogensen, S., Mow, T.
, Pinilla, E., Knudsen, J. S., Hedegaard, E. R., Grunnet, M. & Simonsen, U. (2017).
Novel selective phosphodiesterase type 1 inhibitors cause vasodilatation and lower blood pressure in rats.
British Journal of Pharmacology,
174(15), 2563-2575.
https://doi.org/10.1111/bph.13868
Svendsen, P., Shekhrajka, N., Nielsen, K. L., Vestergaard, P.
, Poulsen, M. Ø., Vistisen, A. K., Munksgaard, P. S., Severinsen, M. T., Jensen, P., Johnsen, H. E., Jakobsen, L. H., Bøgsted, M., Frøkjær, J. B. & El-Galaly, T. C. (2017).
R-CHOP(-like) treatment of diffuse large B-cell lymphoma significantly reduces CT-assessed vertebral bone density: a single center study of 111 patients.
Leukemia & Lymphoma,
58(5), 1105-1113.
https://doi.org/10.1080/10428194.2016.1233543
Hagensen, M. K., Mortensen, M. B., Kjolby, M., Stillits, N. L., Steffensen, L. B. & Bentzon, J. F. (2017).
Reply to "Bioinformatics analysis in type 1 diabetes increases retention of low-density lipoprotein in the atherosclerosis-prone area of the murine aorta".
Atherosclerosis. Supplement,
263, 428-429.
https://doi.org/10.1016/j.atherosclerosis.2017.06.926
Iversen, A. B., Horsman, M. R., Jakobsen, S., Jensen, J. B., Garm, C., Jessen, N., Breining, P., Frøkiær, J. & Busk, M. (2017).
Results from (11)C-metformin-PET scans, tissue analysis and cellular drug-sensitivity assays questions the view that biguanides affects tumor respiration directly.
Scientific Reports,
7(1), 9436. Article 9436.
https://doi.org/10.1038/s41598-017-10010-z
Aarslev, K., Dige, A., Greisen, S. R., Kreutzfeldt, M. H., Jessen, N., Vilstrup, H., Deleuran, B. & Grønbæk, H. (2017).
Soluble programmed death-1 levels are associated with disease activity and treatment response in patients with autoimmune hepatitis.
Scandinavian Journal of Gastroenterology,
52(1), 93-99.
https://doi.org/10.1080/00365521.2016.1233576
Pedersen, M. H., Svart, M. V., Lebeck, J., Bidlingmaier, M.
, Stødkilde-Jørgensen, H., Pedersen, S. B., Møller, N., Jessen, N. & Jørgensen, J. O. L. (2017).
Substrate Metabolism and Insulin Sensitivity During Fasting in Obese Human Subjects: Impact of GH Blockade.
Journal of Clinical Endocrinology and Metabolism,
102(4), 1340-1349.
https://doi.org/10.1210/jc.2016-3835
Hellfritzsch, M.
, Husted, S. E., Grove, E. L., Rasmussen, L., Poulsen, B. K., Johnsen, S. P., Hallas, J. & Pottegård, A. (2017).
Treatment Changes among Users of Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation.
Basic & Clinical Pharmacology & Toxicology,
120(2), 187–194.
https://doi.org/10.1111/bcpt.12664
Nielsen, E. S., Rasmussen, L., Poulsen, M. H.
, Thomsen, P. H., Nørgaard, M. & Laursen, T. (2017).
Trends in Off-Label Prescribing of Sedatives, Hypnotics and Antidepressants among Children and Adolescents - A Danish, Nationwide Register-Based Study.
Basic & Clinical Pharmacology & Toxicology,
120(4), 360-367.
https://doi.org/10.1111/bcpt.12706
Hagensen, M. K., Mortensen, M. B., Kjolby, M., Stillits, N. L., Steffensen, L. B. & Bentzon, J. F. (2017).
Type 1 diabetes increases retention of low-density lipoprotein in the atherosclerosis-prone area of the murine aorta.
Atherosclerosis,
263, 7-14.
https://doi.org/10.1016/j.atherosclerosis.2017.05.019
Kierulf-Lassen, C., Nielsen, P. M., Qi, H., Damgaard, M., Laustsen, C., Pedersen, M., Krag, S., Birn, H., Nørregaard, R. & Jespersen, B. (2017).
Unilateral nephrectomy diminishes ischemic acute kidney injury through enhanced perfusion and reduced pro-inflammatory and pro-fibrotic responses.
PLoS One,
12(12), e0190009. Article e0190009.
https://doi.org/10.1371/journal.pone.0190009
Andersen, C. U., Sonderskov, L. D., Bendstrup, E., Voldby, N., Cass, L., Ayrton, J.
& Hilberg, O. (2017).
Voriconazole Concentrations in Plasma and Epithelial Lining Fluid after Inhalation and Oral Treatment.
Basic & Clinical Pharmacology & Toxicology,
121(5), 430-434.
https://doi.org/10.1111/bcpt.12820
Poulsen, M., Jørgensen, L. K., Sørensen, S., Falgreen, S.
, Bødker, J. S., Laursen, M. B., Schmitz, A., Johnsen, H. E., Dybkær, K. & Bøgsted, M. (2016).
Alternative pre-mRNA splicing leads to potential biomarkers in diffuse large B-cell lymphoma - a systematic review.
Danish Medical Journal,
63(3), Article A5206.
Jakobsen, S., Busk, M., Jensen, J. B.
, Munk, O. L., Zois, N. E.
, Alstrup, A. K. O., Jessen, N. & Frøkiær, J. (2016).
A PET Tracer for Renal Organic Cation Transporters, 11C-metformin: Radiosynthesis and Preclinical Proof-of-Concept Studies.
Journal of Nuclear Medicine,
57(4)(4), 615-621.
https://doi.org/10.2967/jnumed.115.169292
Goettsch, C., Hutscheson, JD., Hagita, S., Rogers, M., Creager, MD., Pham, T., Choi, J., Mlynarchik, AK., Pieper, B.
, Kjølby, M. F., Aikawa, M. & Aikawa, E. (2016).
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification. Atherosclerosis,
251, 109-118.
https://doi.org/10.1016/j.atherosclerosis.2016.06.011
Brock, C., Brock, B., Pedersen, A. G.
, Drewes, A. M., Jessen, N. & Farmer, A. D. (2016).
Assessment of the cardiovascular and gastrointestinal autonomic complications of diabetes.
World Journal of Diabetes,
7(16), 321-32.
https://doi.org/10.4239/wjd.v7.i16.321
Brøsen, K.
, Andersen, S. E., Borregaard, J.
, Christensen, H. R., Christensen, P. M.
, Dalhoff, K. P., Damkier, P., Hallas, J., Heisterberg, J.
, Jessen, N., Jürgens, G., Kampmann, J. P. K.
, Laursen, B. E., Laursen, T., Nielsen, L. P., Poulsen, B. K., Poulsen, H. E.
, Andersen, L. V., Senderovitz, T. & Sonne, J. (2016).
Clinical Pharmacology in Denmark in 2016 - 40 Years with the Danish Society of Clinical Pharmacology and 20 Years as a Medical Speciality.
Basic & Clinical Pharmacology & Toxicology,
119(6), 523-532.
https://doi.org/10.1111/bcpt.12681
Svart, M., Opstrup, U. K., Voss, T., Pedersen, S. B., Johannsen, M., Rittig, N., Poulsen, P. L., Nielsen, T. S.
, Jessen, N. & Møller, N. (2016).
Combined Insulin Deficiency and Endotoxin Exposure Stimulate Lipid Mobilization and Alter Adipose Tissue Signaling in an Experimental Model of Ketoacidosis in Subjects with Type 1 Diabetes: A Randomized, Controlled, Crossover Trial.
Diabetes,
65(5), 1380-1386.
https://doi.org/10.2337/db15-1645
Poulsen, M. Ø., Sinding, M. M., Peters, D., Frøkjær, J. B., Østergaard, L. R., Petersen, A. C., Overgaard, C. & Sørensen, A. N. (2016).
CT angiography of the fetoplacental vasculature in fetal growth restriction. In
Kongres for Medicinsk Studenterforskning, 17.-20. marts 2016, Nyborg, Danmark (pp. 67-68). Article No. p.5-8 Selskab for Medicinsk Studenterforskning.
http://studenterkongres.dk/kms/public_html/2016/abstractbog_2016.pdf
Lerin, C., Goldfine, A. B., Boes, T., Liu, M., Kasif, S., Dreyfuss, J. M., De Sousa-Coelho, A. L., Daher, G., Manoli, I., Sysol, J. R., Isganaitis, E.
, Jessen, N., Goodyear, L. J., Beebe, K., Gall, W., Venditti, C. P. & Patti, M.-E. (2016).
Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism.
Molecular Metabolism,
5(10), 926-936.
https://doi.org/10.1016/j.molmet.2016.08.001
Juul, K. V.
, Jessen, N., Bliwise, D. L., van der Meulen, E. & Nørgaard, J. P. (2016).
Delaying time to first nocturnal void may have beneficial effects on reducing blood glucose levels.
Endocrine,
53(3), 722-729.
https://doi.org/10.1007/s12020-016-0920-y
Sædder, E. A., Lisby, M., Nielsen, L. P., Rungby, J., Andersen, L. V., Bonnerup, D. K. & Brock, B. (2016).
Detection of Patients at High Risk of Medication Errors: Development and Validation of an Algorithm.
Basic & Clinical Pharmacology & Toxicology,
118(2), 143-149.
https://doi.org/10.1111/bcpt.12473
Bak, A. M., Møller, A. B., Vendelbo, M. H., Nielsen, T. S., Viggers, R., Rungby, J., Pedersen, S. B., Jørgensen, J. O. L., Jessen, N. & Møller, N. (2016).
Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast.
American Journal of Physiology: Endocrinology and Metabolism,
311(1), E224-E235.
https://doi.org/10.1152/ajpendo.00464.2015
Christensen, B., Nellemann, B., Jørgensen, J. O. L., Pedersen, S. B. & Jessen, N. (2016).
Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo.
Lipids in Health and Disease,
15(1), Article 160.
https://doi.org/10.1186/s12944-016-0327-z
Dal, J., Lundby Høyer, K., Pedersen, S. B., Erik Magnusson, N., Bjerring, P., Frystyk, J., Møller, N., Jessen, N. & Otto Lunde Jørgensen, J. (2016).
Growth Hormone and Insulin Signaling in Acromegaly: Impact of Surgery versus Somatostatin Analog Treatment.
Endocrinology,
101(10), 3716-3723.
https://doi.org/10.1210/jc.2016-1806
Viborg, S., Søgaard, K. K., Farkas, D. K., Nørrelund, H., Pedersen, L. & Sørensen, H. T. (2016).
Lower Gastrointestinal Bleeding And Risk of Gastrointestinal Cancer.
Clinical and Translational Gastroenterology,
7, e162. Article e161.
https://doi.org/10.1038/ctg.2016.16
Nøhr, M. K., Dudele, A., Poulsen, M. M., Ebbesen, L. H., Radko, Y., Christensen, L. P.
, Jessen, N., Richelsen, B., Lund, S. & Pedersen, S. B. (2016).
LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol.
PLoS One,
11(1), Article e0146840.
https://doi.org/10.1371/journal.pone.0146840
Klinger, S. C., Højland, A., Jain, S.
, Kjolby, M., Madsen, P., Svendsen, A. D., Olivecrona, G., Bonifacino, J. S.
& Nielsen, M. S. (2016).
Polarized Trafficking of the Sorting Receptor SorLA in Neurons and MDCK Cells.
FEBS journal,
283(13), 2476–2493.
https://doi.org/10.1111/febs.13758
Soerensen, A. L., Nielsen, L. P., Poulsen, B. K., Lisby, M. & Mainz, J. (2016).
Potentially inappropriate prescriptions in patients admitted to a psychiatric hospital.
Nordic Journal of Psychiatry,
70(5), 365-373.
https://doi.org/10.3109/08039488.2015.1127996
Jessen, N., Nielsen, T. S., Vendelbo, M. H., Viggers, R., Støen, O.-G., Evans, A.
& Frøbert, O. (2016).
Pronounced expression of the lipolytic inhibitor G0/G1 Switch Gene 2 (G0S2) in adipose tissue from brown bears (Ursus arctos) prior to hibernation.
Physiological Reports,
4(8), e12781 . Article e12781.
https://doi.org/10.14814/phy2.12781
Rittig, N., Bach, E., Thomsen, H. H., Pedersen, S. B., Nielsen, T. S.
, Jørgensen, J. O. L., Jessen, N. & Møller, N. (2016).
Regulation of Lipolysis and Adipose Tissue Signaling during Acute Endotoxin-Induced Inflammation: A Human Randomized Crossover Trial.
PLoS One,
11(9), Article e0162167.
https://doi.org/10.1371/journal.pone.0162167
Kristensen, M. L. V., Lassen, C. K., Nielsen, P. M., Krag, S., Birn, H., Nejsum, L. N. & Nørregaard, R. (2016).
Remote ischemic perconditioning attenuates ischemia/reperfusion-induced downregulation of AQP2 in rat kidney.
Physiological Reports,
4(13), Article e12865.
https://doi.org/10.14814/phy2.12865
Pedersen, L. H., Jensen, J. B., Wogensen, L., Munk, O. L., Jessen, N., Frøkiær, J. & Jakobsen, S. (2016).
Renal PET-imaging with 11C-metformin in a transgenic mouse model for chronic kidney disease.
EJNMMI Research,
6(1), Article 54.
https://doi.org/10.1186/s13550-016-0211-x
Christensen, M., Jensen, J. B., Jakobsen, S., Jessen, N., Frøkiær, J., Kemp, B. E., Marciszyn, A. L., Li, H., Pastor-Soler, N. M., Hallows, K. R.
& Nørregaard, R. (2016).
Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 &2 and AMP-activated Protein Kinase in the Kidney.
Scientific Reports,
6, Article 35952.
https://doi.org/10.1038/srep35952
Rittig, N., Bach, E., Thomsen, H. H., Johannsen, M., Jørgensen, J. O., Richelsen, B., Jessen, N. & Møller, N. (2016).
Reply: Letter to the editor - A dietary amino acid load causes a transient decrease in the function of human neutrophil granulocytes.
Clinical Nutrition,
35(3), 771.
https://doi.org/10.1016/j.clnu.2016.01.024
Grønbaek, H., Kreutzfeldt, M. H., Kazankov, K., Jessen, N., Sandahl, T., Hamilton-Dutoit, S., Vilstrup, H. & Møller, H. J. (2016).
Single-centre experience of the macrophage activation marker soluble (s)CD163 - associations with disease activity and treatment response in patients with autoimmune hepatitis.
Alimentary Pharmacology and Therapeutics,
44(10), 1062-1070.
https://doi.org/10.1111/apt.13801