Publications 2022

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Andersen, C. U., Nielsen, L. P., Møller, J. M. & Olesen, A. E. (2022). Acute drug poisonings leading to hospitalization. Basic and Clinical Pharmacology and Toxicology, 130(2), 328-336. https://doi.org/10.1111/bcpt.13688

Rahbani, J. F., Scholtes, C., Lagarde, D. M., Hussain, M. F., Roesler, A., Dykstra, C. B., Bunk, J., Samborska, B., O'Brien, S. L., Tripp, E., Pacis, A., Angueira, A. R., Johansen, O. S., Cinkornpumin, J., Hossain, I., Lynes, M. D., Zhang, Y., White, A. P., Pastor, W. A. ... Kazak, L. (2022). ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP. Nature Metabolism, 4(11), 1459-1473. https://doi.org/10.1038/s42255-022-00667-w

Jensen, J. B., Dollerup, O. L., Møller, A. B., Billeskov, T. B., Dalbram, E., Chubanava, S., Damgaard, M. V., Dellinger, R. W., Trošt, K., Moritz, T., Ringgaard, S., Møller, N., Treebak, J. T., Farup, J. & Jessen, N. (2022). A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals. JCI Insight, 7(19), Article e158314. https://doi.org/10.1172/jci.insight.158314

Wang, T., Nielsen, K. L., Frisch, K., Lassen, J. K., Nielsen, C. B., Andersen, C. U., Villesen, P., Andreasen, M. F., Hasselstrøm, J. B. & Johannsen, M. (2022). A Retrospective Metabolomics Analysis of Gamma-Hydroxybutyrate in Humans: New Potential Markers and Changes in Metabolism Related to GHB Consumption. Frontiers in Pharmacology, 13, Article 816376. https://doi.org/10.3389/fphar.2022.816376

Ren, T., Zhang, J., Yu, Y., Pedersen, L. H., Wang, H., Li, F., Henriksen, T. B. & Li, J. (2022). Association of labour epidural analgesia with neurodevelopmental disorders in offspring: a Danish population-based cohort study. British Journal of Anaesthesia, 128(3), 513-521. https://doi.org/10.1016/j.bja.2021.10.042

Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L. P. M. H., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W. ... Luo, Y. (2022). Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level (Nature Communications, (2022), 13, 1, (3620), 10.1038/s41467-022-31388-z). Nature Communications, 13(1), Article 6748. https://doi.org/10.1038/s41467-022-34498-w

Jankowski, V., Saritas, T., Kjolby, M., Hermann, J., Speer, T., Himmelsbach, A., Mahr, K., Heuschkel, M. A., Schunk, S. J., Thirup, S., Winther, S., Bottcher, M., Nyegard, M., Nykjaer, A., Kramann, R., Kaesler, N., Jankowski, J., Floege, J., Marx, N. & Goettsch, C. (2022). Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease. Kidney International, 101(3), 574-584. https://doi.org/10.1016/j.kint.2021.10.018

Knudsen, J. S., Knudsen, S. S., Hulman, A., Witte, D. R., Gregg, E. W., Lauritzen, T., Pedersen, L., Sørensen, H. T. & Thomsen, R. W. (2022). Changes in type 2 diabetes incidence and mortality associated with introduction of HbA1c as diagnostic option: A Danish 24-year population-based study. The Lancet Regional Health - Europe, 14, Article 100291. https://doi.org/10.1016/j.lanepe.2021.100291

Klug, T. E., Andersen, C., Hahn, P., Danstrup, C. S., Petersen, N. K., Mikkelsen, S., Døssing, H., Christensen, A.-L., Rusan, M., Kjeldsen, A. & Greve, T. (2022). Clinical evaluation of antibiotic regimens in patients with surgically verified parapharyngeal abscess: a prospective observational study. European Archives of Oto-Rhino-Laryngology, 279(4), 2057-2067. https://doi.org/10.1007/s00405-021-06962-8

Andersen, F. D., Joca, S., Hvingelby, V., Arjmand, S., Pinilla, E., Comerma Steffensen, S. G., Simonsen, U. & Andersen, C. U. (2022). Combined effects of quetiapine and opioids: A study of autopsy cases, drug users and sedation in rats . Addiction Biology (Online), 27(5), Article e13214. https://doi.org/10.1111/adb.13214

Benfield, T., Bodilsen, J., Brieghel, C., Harboe, Z. B., Helleberg, M., Holm, C., Israelsen, S. B., Jensen, J., Jensen, T. Ø., Johansen, I. S., Johnsen, S., Madsen, B. L., Lundgren, J., Meyer, C. N., Mohey, R., Pedersen, L., Nielsen, H., Nielsen, S. L., Obel, N. ... Christensen, H. R. (2022). Correction to: Improved Survival Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Treated With Remdesivir and Dexamethasone. A Nationwide Population-Based Cohort Study (Clinical Infectious Diseases (2021) 73:11 (2031-2036) DOI: 10.1093/cid/ciab536). Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 74(10), 1889. https://doi.org/10.1093/cid/ciac243

Sedgwick, P. M., Hammer, A., Kesmodel, U. S. & Pedersen, L. H. (2022). Current controversies: Null hypothesis significance testing. Acta Obstetricia et Gynecologica Scandinavica, 101(6), 624-627. https://doi.org/10.1111/aogs.14366

Hjelholt, T. J., Johnsen, S. P., Brynningsen, P. K., Knudsen, J. S., Prieto-Alhambra, D. & Pedersen, A. B. (2022). Development and validation of a model for predicting mortality in patients with hip fracture. Age and Ageing, 51(1), Article afab233. https://doi.org/10.1093/ageing/afab233

Frøbert, A. M., Toews, J. N. C., Nielsen, C. G., Brohus, M., Kindberg, J., Jessen, N., Fröbert, O., Hammond, G. L. & Overgaard, M. T. (2022). Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats. Physiological and Biochemical Zoology, 95(5), 365-378. https://doi.org/10.1086/721154

Møller, J. E., Henriksen, J., Søjnæs, C. & Brøgger, M. N. (2022). Doctors' experiences of earlier mandatory postgraduate communication skills training: a qualitative study. International Journal of Medical Education, 13, 47-55. https://doi.org/10.5116/ijme.6213.7ee7

Lauritsen, K. M., Voigt, J. H., Pedersen, S. B., Hansen, T. K., Møller, N., Jessen, N., Gormsen, L. C. & Søndergaard, E. (2022). Effects of SGLT2 inhibition on lipid transport in adipose tissue in type 2 diabetes. Endocrine Connections, 11(4), Article e210558. https://doi.org/10.1530/EC-21-0558

Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L. P. M. H., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W. ... Luo, Y. (2022). Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level. Nature Communications, 13(1), Article 3620. https://doi.org/10.1038/s41467-022-31388-z

Mains Balle, C., Gravholt, C. H., Andersen, N. H., Hvas, A.-M., Laursen, T. & Hansen, M. (2022). Estrogen replacement therapy in women with Turner syndrome.

Thomsen, R. W., Christensen, L. W. B., Kahlert, J., Knudsen, J. S., Ustyugova, A., Sandgaard, S., Holmgaard, P., Ehlers, L. H. & Sørensen, H. T. (2022). Healthcare Resource Utilization and Costs for Empagliflozin Versus Glucagon-Like Peptide-1 Receptor Agonists in Routine Clinical Care in Denmark. Diabetes therapy, 13(11-12), 1891-1906. https://doi.org/10.1007/s13300-022-01323-y

Brandt, C. B., Fonager, S. V., Haskó, J., Helmig, R. B., Degn, S., Bolund, L., Jessen, N., Lin, L. & Luo, Y. (2022). HIF1A Knockout by Biallelic and Selection-Free CRISPR Gene Editing in Human Primary Endothelial Cells with Ribonucleoprotein Complexes. Biomolecules, 13(1), Article 23. https://doi.org/10.3390/biom13010023

Cen, H. H., Hussein, B., Botezelli, J. D., Wang, S., Zhang, J. A., Noursadeghi, N., Jessen, N., Rodrigues, B., Timmons, J. A. & Johnson, J. D. (2022). Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance. The FASEB Journal, 36(1), Article e22088. https://doi.org/10.1096/fj.202100497RR

Sørup, S., Darvalics, B., Knudsen, J. S., Rasmussen, A. S., Hjorth, C. F., Vestergaard, S. V., Khalil, A. A., Russo, L., Oksen, D., Boutmy, E., Verpillat, P., Rørth, M. & Cronin-Fenton, D. (2022). Identifying Valid Algorithms for Number of Lines of Anti-Neoplastic Therapy in the Danish National Patient Registry Among Patients with Advanced Ovarian, Gastric, Renal Cell, Urothelial, and Non-Small Cell Lung Cancer Attending a Danish University Hospital. Clinical Epidemiology, 14, 159-171. https://doi.org/10.2147/CLEP.S342238

Mikkelsen, R. R., Hundahl, M. P., Torp, C. K., Rodríguez-Carrio, J., Kjolby, M., Bruun, J. M. & Kragstrup, T. W. (2022). Immunomodulatory and immunosuppressive therapies in cardiovascular disease and type 2 diabetes mellitus: A bedside-to-bench approach. European Journal of Pharmacology, 925, Article 174998. https://doi.org/10.1016/j.ejphar.2022.174998

Jensen, M. E. J., Gregersen, M., Lassen, C. K. & Foss, A.-C. H. (2022). Interventions to Prevent Medication-related Deterioration in Acutely Hospitalized Older Patients: Preliminary Data from a Scoping Review of Clinical Studies. Abstract from The 18th International Congress, London, United Kingdom.

Thomsen, H. H., Olesen, J. F., Aagaard, R., Nielsen, B. R. R., Voss, T. S., Svart, M. V., Johannsen, M., Jessen, N., Jorgensen, J. O. L., Rittig, N., Bach, E. & Moller, N. (2022). Investigating effects of sodium beta-hydroxybutyrate on metabolism in placebo-controlled, bilaterally infused human leg with focus on skeletal muscle protein dynamics. Physiological Reports, 10(16), Article e15399. https://doi.org/10.14814/phy2.15399

Sandbæk, A., Møller, M. C. R., Bro, F., Høj, K., Due Christensen, L. & Mygind, A. (2022). Involving patients in medicines optimisation in general practice: a development study of the “PREparing Patients for Active Involvement in medication Review” (PREPAIR) tool. BMC Primary Care, 23(1), Article 122. https://doi.org/10.1186/s12875-022-01733-8

Patel, A., Frikke-Schmidt, H., Bezy, O., Sabatini, P. V., Rittig, N., Jessen, N., Myers, M. G. & Seeley, R. J. (2022). LPS induces rapid increase in GDF15 levels in mice, rats and humans but is not required for anorexia in mice. A J P: Gastrointestinal and Liver Physiology (Online), 322(2), G247-G255. https://doi.org/10.1152/ajpgi.00146.2021

Pan, X., Qu, K., Yuan, H., Xiang, X., Anthon, C., Pashkova, L., Liang, X., Han, P., Corsi, G. I., Xu, F., Liu, P., Zhong, J., Zhou, Y., Ma, T., Jiang, H., Liu, J., Wang, J., Jessen, N., Bolund, L. ... Luo, Y. (2022). Massively targeted evaluation of therapeutic CRISPR off-targets in cells. Nature Communications, 13(1), Article 4049. https://doi.org/10.1038/s41467-022-31543-6

Ostenfeld, A., Petersen, T. S., Pedersen, L. H., Westergaard, H. B., Løkkegaard, E. C. & Andersen, J. T. (2022). Mirtazapine exposure in pregnancy and fetal safety: A nationwide cohort study. Acta Psychiatrica Scandinavica, 145(6), 557-567. https://doi.org/10.1111/acps.13431

Rusan, M., Ovesen, T. O. K., Fuursted, K. & Ovesen, T. (2022). Næsen kan være fokus for behandling af og profylakse mod COVID-19. Ugeskrift for Læger, 183(2), Article V05210442.

Arbejdsgruppen for den nationale kliniske anbefaling for behandling med melatonin ved søvnforstyrrelser hos børn og unge (2022). National Klinisk Anbefaling: Behandling med melatonin ved søvnforstyrrelser hos børn og unge. Sundhedsstyrelsen. https://www.sst.dk/da/Udgivelser/2022/NKA_-Behandling-med-melatonin-ved-soevnforstyrrelser-hos-boern-og-unge

Kolding, L., Ehrenstein, V., Pedersen, L., Sandager, P., Petersen, O. B., Uldbjerg, N. & Pedersen, L. H. (2022). Obstetric care for women that use antidepressants in pregnancy. BJOG: An International Journal of Obstetrics and Gynaecology, 129(1), 172-172. https://doi.org/10.1111/1471-0528.16918

Pedersen, M. G. B., Søndergaard, E., Nielsen, C. B., Johannsen, M., Gormsen, L. C., Møller, N., Jessen, N. & Rittig, N. (2022). Oral lactate slows gastric emptying and suppresses appetite in young males. Clinical Nutrition, 41(2), 517-525. https://doi.org/10.1016/j.clnu.2021.12.032

Steffensen, E. H., Rosvig, L. H., Santoro, S., Pedersen, L. H., Vogel, I. & Lou, S. (2022). Parenting a child with Down syndrome. A qualitative study of everyday practices in Danish families. Journal of Genetic Counseling, 31(3), 758-770. https://doi.org/10.1002/jgc4.1542

Sakamoto, K. & Jessen, N. (2022). PEN2: Metformin's new partner at lysosome. Cell Research, 32(6), 507–508. https://doi.org/10.1038/s41422-022-00661-7

Thunbo, M. Ø., Vendelbo, J. H., Volqvartz, T. P. M., Witte, D. R., Larsen, A. & Pedersen, L. H. (2022). Polypharmacy in polymorbid pregnancies and the risk of congenital malformations: a systematic review. Basic & Clinical Pharmacology & Toxicology, 130(3), 394-414. https://doi.org/10.1111/bcpt.13695

Pedersen, L. H. (2022). Pregnancy and perinatal pharmacology: A paradigm shift is needed. Acta Obstetricia et Gynecologica Scandinavica, 101(2), 166-167. https://doi.org/10.1111/aogs.14313

Tomar, N., Uldbjerg, C. S., Bech, B. H., Burgner, D. P., Pedersen, L. H. & Miller, J. E. (2022). Prenatal antibiotic exposure and birth weight. Pediatric Obesity, 17(2), Article e12831. https://doi.org/10.1111/ijpo.12831

Paust, A., Mygind, A., Høj, K., Christensen, L. D. & Bro, F. (2022). PREPAIR - et redskab til at forberede og involvere patienter i medicinsamtalen. Rationel Farmakoterapi, 7. https://www.sst.dk/-/media/Udgivelser/2022/Rationel-Farmakoterapi/7/Rationel-farmakoterapi-7-2022.ashx?sc_lang=da&hash=39BE1A41BCAB69D3D63D95278445493E

Arlien-Søborg, M. C., Dal, J., Madsen, M. A., Høgild, M. L., Hjelholt, A. J., Pedersen, S. B., Møller, N., Jessen, N. & Jørgensen, J. O. L. (2022). Reversible insulin resistance in muscle and fat unrelated to the metabolic syndrome in patients with acromegaly. EBioMedicine, 75, Article 103763. https://doi.org/10.1016/j.ebiom.2021.103763

Rohde, C., Nielsen, J. S., Knudsen, J. S., Thomsen, R. W. & Østergaard, S. D. (2022). Risk factors associated with mortality among individuals with type 2 diabetes and depression across two cohorts. European Journal of Endocrinology, 187(4), 567-577. https://doi.org/10.1530/EJE-22-0466

Hammer, A., Haubjerg, L., Gibrael, H. S., Winther, A., Pedersen, L. H., Fuglsang, K. & Jensen, P. T. (2022). Screening, diagnostik og behandling af cervixcancer i graviditeten. Ugeskrift for Læger, 184(35), Article V03220187 .

Olesen, A. E., Schacksen, C. S., Nielsen, I. M., Nielsen, L. P., Andersen, S. & Andersen, C. U. (2022). Significantly higher use of polypharmacy in elderly with hip fracture treated with psychotropics. Danish Medical Journal, 69(10), Article A12210945.

Pedersen, A. K. N., Hage, C., Jessen, N., Mellbin, L. & Bjerre, M. (2022). Sitagliptin reduces FAP-activity and increases intact FGF21 levels in patients with newly detected glucose abnormalities. Molecular and Cellular Endocrinology, 556, Article 111738. https://doi.org/10.1016/j.mce.2022.111738

Hølmkjær, P., Vermehren, C., Holm, A., Rozing, M. P., Høj, K. & Overbeck, G. (2022). Tailoring a complex intervention to reduce antidepressants in institutionalized older persons with dementia. BMC Health Services Research, 22(1), Article 1582. https://doi.org/10.1186/s12913-022-08961-9

Ahring, K. K., Dagnæs-Hansen, F., Brüel, A., Christensen, M., Jensen, E., Jensen, T. G., Johannsen, M., Johansen, K. S., Lund, A. M., Madsen, J. G., Brøndum-Nielsen, K., Pedersen, M., Sørensen, L. K., Kjolby, M. & Møller, L. B. (2022). The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model. PLOS ONE, 17(1), Article e0261150. https://doi.org/10.1371/journal.pone.0261150

Lauritzen, E. S., Kampmann, U., Pedersen, M. G. B., Christensen, L.-L., Jessen, N., Møller, N. & Støy, J. (2022). Three months of melatonin treatment reduces insulin sensitivity in patients with type 2 diabetes - a randomized placebo-controlled crossover trial. Journal of Pineal Research, 73(1), Article e12809. https://doi.org/10.1111/jpi.12809

Christensen, D. H., Nicolaisen, S. K., Ahlqvist, E., Stidsen, J. V., Nielsen, J. S., Hojlund, K., Olsen, M. H., García-Calzón, S., Ling, C., Rungby, J., Brandslund, I., Vestergaard, P., Jessen, N., Hansen, T., Brøns, C., Beck-Nielsen, H., Sørensen, H. T., Thomsen, R. W. & Vaag, A. (2022). Type 2 diabetes classification: a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort. BMJ Open Diabetes Research & Care, 10(2), Article e002731. https://doi.org/10.1136/bmjdrc-2021-002731

Kristensen, F. P. B., Christensen, D. H., Callaghan, B. C., Stidsen, J., Nielsen, J. S., Højlund, K., Staehelin-Jensen, T., Vestergaard, P., Jessen, N. & Thomsen, RW. (2022). Type 2 diabetes phenotypes and polyneuropathy: a prevalence study in the DD2 Cohort. Diabetologia, 65(Suppl. 1), Article 191.

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Revised 15.06.2022

Ellen Kristensen