Kampmann, U., Lauritzen, E. S., Grarup, N.
, Jessen, N., Hansen, T.
, Møller, N. & Støy, J. (2021).
Acute metabolic effects of melatonin - a randomized crossover study in healthy young men.
Journal of Pineal Research,
70(2), Article e12706.
https://doi.org/10.1111/jpi.12706
Amadid, H., Rønn, P. F., Bekker-Nielsen Dunbar, M.
, Knudsen, J. S., Carstensen, B., Persson, F.
& Jørgensen, M. E. (2021).
A large remaining potential in lipid-lowering drug treatment in the type 2 diabetes population: A Danish nationwide cohort study.
Diabetes, Obesity and Metabolism,
23(10), 2354-2363.
https://doi.org/10.1111/dom.14478
Uldbjerg, C. S., Miller, J. E., Burgner, D.
, Pedersen, L. H. & Bech, B. H. (2021).
Antibiotic exposure during pregnancy and childhood asthma: a national birth cohort study investigating timing of exposure and mode of delivery.
Archives of Disease in Childhood,
106(9), 888-894.
https://doi.org/10.1136/archdischild-2020-319659
Kolding, L., Ehrenstein, V., Pedersen, L., Sandager, P., Petersen, OB., Uldbjerg, N. & Pedersen, LH. (2021).
Antidepressant use in pregnancy and severe cardiac malformations: Danish register-based study.
BJOG: An International Journal of Obstetrics & Gynaecology,
128(12), 1949-1957.
https://doi.org/10.1111/1471-0528.16772
Laustsen, A., van der Sluis, R. M., Gris Oliver, A., Sanchez Hernandez, S., Cemalovic, E., Tang, H. Q., Pedersen, L. H., Uldbjerg, N., Jakobsen, M. R. & Bak, R. (2021).
Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells.
eLife,
10, Article e65528.
https://doi.org/10.7554/eLife.65528
Kolding, L., Ehrenstein, V., Pedersen, L., Sandager, P., Petersen, O. B., Uldbjerg, N. & Pedersen, L. (2021).
Associations Between ADHD Medication Use in Pregnancy and Severe Malformations Based on Prenatal and Postnatal Diagnoses: A Danish Registry-Based Study.
Journal of Clinical Psychiatry,
82(1), Article 20m13458.
https://doi.org/10.4088/JCP.20m13458
Jensen, N. B., Justesen, S. D., Larsen, A., Ernst, E. & Pedersen, L. H. (2021).
A systematic overview of the spermatotoxic and genotoxic effects of methotrexate, ganciclovir and mycophenolate mofetil.
Acta Obstetricia et Gynecologica Scandinavica,
100(9), 1557-1580.
https://doi.org/10.1111/aogs.14151
Tveden-Nyborg, P., Bergmann, T. K.
, Jessen, N., Simonsen, U. & Lykkesfeldt, J. (2021).
BCPT policy for experimental and clinical studies.
Basic & Clinical Pharmacology & Toxicology,
128(1), 4-8.
https://doi.org/10.1111/bcpt.13492Breining, P., Frølund, A. L.
, Højen, J. F., Gunst, J. D., Staerke, N. B., Sædder, E. A., Cases-Thomas, M., Little, P.
, Nielsen, L. P., Søgaard, O. S. & Kjolby, M. (2021).
Camostat mesylate against SARS-CoV-2 and COVID-19-Rationale, dosing and safety.
Basic & Clinical Pharmacology & Toxicology,
128(2), 204-212.
https://doi.org/10.1111/bcpt.13533
Hoffmann, M., Hofmann-Winkler, H., Smith, J. C., Krüger, N., Arora, P.
, Sørensen, L. K., Søgaard, O. S., Hasselstrøm, J. B., Winkler, M., Hempel, T., Raich, L., Olsson, S., Danov, O., Jonigk, D., Yamazoe, T., Yamatsuta, K., Mizuno, H., Ludwig, S., Noé, F. ... Pöhlmann, S. (2021).
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
EBioMedicine,
65, Article 103255.
https://doi.org/10.1016/j.ebiom.2021.103255Thomsen, R. W., Knudsen, J. S., Kahlert, J., Baggesen, L. M., Lajer, M., Holmgaard, P. H., Vedin, O., Ustyugova, A.
& Sørensen, H. T. (2021).
Cardiovascular events, acute hospitalizations, and mortality in patients with type 2 diabetes mellitus who initiate empagliflozin versus liraglutide: A comparative effectiveness study.
Journal of the American Heart Association,
10(11), Article e019356.
https://doi.org/10.1161/JAHA.120.019356
Rhein, P., Desjardins, E. M., Rong, P., Ahwazi, D., Bonhoure, N., Stolte, J., Santos, M. D., Ovens, A. J., Ehrlich, A. M., Sanchez Garcia, J. L., Ouyang, Q., Yabut, J. M.
, Kjolby, M. F., Membrez, M.
, Jessen, N., Oakhill, J. S., Treebak, J. T., Maire, P., Scott, J. W. ... Sakamoto, K. (2021).
Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle.
Molecular Metabolism,
51, Article 101228.
https://doi.org/10.1016/j.molmet.2021.101228Markvardsen, L. K., Sønderskov, L. D., Wandall-Frostholm, C., Pinilla, E., Prat-Duran, J., Aalling, M., Mogensen, S., Andersen, C. U. & Simonsen, U. (2021).
Cystamine Treatment Fails to Prevent the Development of Pulmonary Hypertension in Chronic Hypoxic Rats.
Journal of Vascular Research,
58(4), 237-251.
https://doi.org/10.1159/000515511
Sørensen, L. K., Hasselstrøm, J. B., Damsgaard Gunst, J., Søgaard, O. S. & Kjolby, M. (2021).
Determination of camostat and its metabolites in human plasma – Preservation of samples and quantification by a validated UHPLC-MS/ MS method.
Clinical Biochemistry,
96, 56-62.
https://doi.org/10.1016/j.clinbiochem.2021.07.007
Sandbæk, A., Møller, M. C. R., Bro, F., Høj, K., Christensen, L. D. & Mygind, A. (2021).
Developing a tool for patient involvement in general practice: The preparing patients for active involvement in medication review (PREPAIR) tool (Conference Abstract).
European Journal of General Practice,
27(1), 307.
https://doi.org/10.1080/13814788.2021.1976752
Hjelholt, T. J., Johnsen, S. P.
, Brynningsen, P. K., Knudsen, J. S., Prieto-Alhambra, D.
& Pedersen, A. B. (2021).
Development and validation of a prediction model for mortality in patients with hip fracture: Population-based cohort study. Poster session presented at ICPE all acces 2021.
Hjelholt, T. J., Johnsen, S. P.
, Brynningsen, P. K., Knudsen, J. S., Prieto-Alhambra, D.
& Pedersen, A. B. (2021).
Development and validation of a prediction model for mortality in patients with hip fracture: Population-based cohort study.
Pharmacoepidemiology and Drug Safety,
30(S1), 193-194.
https://onlinelibrary.wiley.com/toc/10991557/2021/30/S1
Rittig, N., Aagaard, N. K., Villadsen, G. E., Sandahl, T. D., Jessen, N., Grønbaek, H. & George, J. (2021).
Editorial: metformin for portal hypertension-old dog, new tricks? Authors' reply.
Alimentary Pharmacology and Therapeutics,
54(3), 347-347.
https://doi.org/10.1111/apt.16503
Cham, L. B., Pahus, M. H., Grønhøj, K.
, Olesen, R., Ngo, H., Monrad, I., Kjolby, M., Tolstrup, M., Gunst, J. D. & Søgaard, O. S. (2021).
Effect of age on innate and adaptive immunity in hospitalized covid-19 patients.
Journal of Clinical Medicine,
10(20), Article 4798.
https://doi.org/10.3390/jcm10204798
Gunst, J. D., Staerke, N. B., Pahus, M. H., Kristensen, L. H., Bodilsen, J., Lohse, N.
, Dalgaard, L. S., Brønnum, D.
, Fröbert, O., Hønge, B., Johansen, I. S.
, Monrad, I., Erikstrup, C., Rosendal, R., Vilstrup, E., Mariager, T., Bove, D. G.
, Offersen, R., Shakar, S.
... Søgaard, O. S. (2021).
Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial. EClinicalMedicine,
35, Article 100849.
https://doi.org/10.1016/j.eclinm.2021.100849
Andersen, C. U., Strandhave, C., Thaarup, M., Poulsen, M. B., Andersen, S. & Olesen, A. E. (2021).
Elderly patients with hip fracture and subnormal renal function have inadequate response to vitamin D supplementation.
PharmaNutrition,
17, Article 100274.
https://doi.org/10.1016/j.phanu.2021.100274
Sundelin, E., Jensen, J. B., Jakobsen, S., Gormsen, L. C. & Jessen, N. (2021).
Erratum to: "Metformin Biodistribution: A Key to Mechanisms of Action?": A Key to Mechanisms of Action? (vol 105, pg 3374, 2020).
Journal of Clinical Endocrinology and Metabolism,
106(4), E1935-E1935.
https://doi.org/10.1210/clinem/dgaa907
Monti, G., Kjolby, M., Jensen, A. M. G., Allen, M., Reiche, J.
, Møller, P. L., Comaposada-Baró, R., Zolkowski, B. E., Vieira, C., Jørgensen, M. M., Holm, I. E., Valdmanis, P. N.
, Wellner, N., Vægter, C. B., Lincoln, S. J.
, Nykjær, A., Ertekin-Taner, N., Young, J. E.
, Nyegaard, M. & Andersen, O. M. (2021).
Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease.
Acta Neuropathologica Communications,
9(1), Article 43.
https://doi.org/10.1186/s40478-021-01140-7
Høj, K., Pedersen, H. S., Lundberg, A. S. B., Bro, F., Nielsen, L. P. & Sædder, E. A. (2021).
External validation of the Medication Risk Score in polypharmacy patients in general practice: A tool for prioritizing patients at greatest risk of potential drug-related problems.
Basic & Clinical Pharmacology & Toxicology,
129(4), 319-331.
https://doi.org/10.1111/bcpt.13636
Hummelshøj, N. E., Dam, G., Pedersen, L. H., Hjelholt, A. & Villadsen, G. E. (2021).
First-generation somatostatin ligand receptor treatment in a pregnant patient with a neuroendocrine tumor with liver metastases.
Endocrinology, Diabetes and Metabolism Case Reports,
2021(1), Article 21-0126.
https://doi.org/10.1530/EDM-21-0126
Arendt, L. H., Pedersen, L. H., Pedersen, L., Ovesen, P. G., Henriksen, T. B., Lindhard, M. S., Olsen, J., Sørensen, H. T. & Ramlau-Hansen, C. H. (2021).
Glycemic control in pregnancies complicated by pre-existing diabetes mellitus and congenital malformations: A danish population-based study.
Clinical epidemiology,
13, 615-626.
https://doi.org/10.2147/CLEP.S298748
Andersen, S. U., Chakraborty, T., Chen, W., Chen, X.-M., Chen, Y., Hansen, M., Huang, K., Hubner, C. A., Jensen, T. E.
, Jessen, N., Kaufmann, S. H. E., Lee, J.-Y., Li, B., Li, J., Li, J., Li, Q., Li, Y.
, Lindner, P., Liu, W. ... Zong, W.-X. (2021).
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Autophagy,
17(1), 1-382.
https://doi.org/10.1080/15548627.2020.1797280
Bengtsen, M. B., Knudsen, J. S., Bengtsen, M. B., Møller, N. & Thomsen, RW. (2021).
Hospitalization for hypoglycaemia in people with diabetes in Denmark, 1997-2017: Time trends in incidence and HbA1c and glucose-lowering drug use before and after hypoglycaemia.
Endocrinology, Diabetes & Metabolism,
4(3), Article e00227.
https://doi.org/10.1002/edm2.227
Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G.
, Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H.
... Jessen, N. (2021).
Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients.
Cell Metabolism,
33(11), 2201-2214.e10.
https://doi.org/10.1016/j.cmet.2021.10.001
Bengtsen, M. B., Hansen, E. S. S., Tougaard, R. S., Lyhne, M. D., Rittig, N. F., Støy, J., Jessen, N., Mariager, C. Ø., Stødkilde-Jørgensen, H., Møller, N. & Laustsen, C. (2021).
Hyperpolarized [1-
13C]pyruvate combined with the hyperinsulinaemic euglycaemic and hypoglycaemic clamp technique in skeletal muscle in a large animal model.
Experimental Physiology,
106(12), 2412-2422.
https://doi.org/10.1113/EP089782
Benfield, T., Bodilsen, J., Brieghel, C., Harboe, Z. B., Helleberg, M., Holm, C., Israelsen, S. B., Jensen, J., Jensen, T. Ø., Johansen, I. S., Johnsen, S., Madsen, B. L., Lundgren, J., Meyer, C. N.
, Mohey, R., Pedersen, L. M., Nielsen, H., Nielsen, S. L., Obel, N. ... Christensen, H. R. (2021).
Improved Survival Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Treated With Remdesivir and Dexamethasone. A Nationwide Population-Based Cohort Study: A nationwide population-based cohort study.
Clinical Infectious Diseases,
73(11), 2031-2036.
https://doi.org/10.1093/cid/ciab536Basse, A. L., Agerholm, M.
, Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M.
, Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S. ... Treebak, J. T. (2021).
Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity.
Molecular Metabolism,
53, Article 101271.
https://doi.org/10.1016/j.molmet.2021.101271Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, R. G., Pers, T. H.
, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N. (2021).
Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors and macrophages from human skeletal muscle biopsies.
American journal of physiology. Cell physiology,
321(2), C257-C268.
https://doi.org/10.1152/ajpcell.00127.2021
Larsen, A. H., Wiggers, H., Dollerup, O. L., Jespersen, N. R., Hansson, N. H., Frøkiær, J., Brøsen, K.
, Nørrelund, H., Bøtker, H. E., Møller, N. & Jessen, N. (2021).
Metformin Lowers Body Weight But Fails to Increase Insulin Sensitivity in Chronic Heart Failure Patients without Diabetes: a Randomized, Double-Blind, Placebo-Controlled Study.
Cardiovascular Drugs and Therapy,
35(3), 491-503.
https://doi.org/10.1007/s10557-020-07050-5
Rittig, N., Aagaard, N. K., Sundelin, E., Villadsen, G. E., Sandahl, T. D., Holst, J. J., Hartmann, B., Brøsen, K.
, Grønbaek, H. & Jessen, N. (2021).
Metformin stimulates intestinal glycolysis and lactate release: A single-dose study of metformin in patients with intrahepatic portosystemic stent.
Clinical Pharmacology and Therapeutics,
110(5), 1329-1336.
https://doi.org/10.1002/cpt.2382
Klug, T. E., Greve, T., Andersen, C., Hahn, P., Danstrup, C., Petersen, N. K., Ninn-Pedersen, M.
, Mikkelsen, S., Pauli, S., Fuglsang, S., Døssing, H., Christensen, A.-L.
, Rusan, M. & Kjeldsen, A. (2021).
Microbiology of parapharyngeal abscesses in adults: in search of the significant pathogens.
European Journal of Clinical Microbiology & Infectious Diseases,
40(7), 1461-1470.
https://doi.org/10.1007/s10096-021-04180-y
Gyldenkerne, C., Knudsen, J. S., Olesen, K. K. W., Sørensen, H. T., Bøtker, H. E., Thomsen, R. W. & Maeng, M. (2021).
Nationwide Trends in Cardiac Risk and Mortality in Patients With Incident Type 2 Diabetes: A Danish Cohort Study.
Diabetes Care,
44(10), 2353-2360.
https://doi.org/10.2337/dc21-0383
Svart, M., Rittig, N., Pedersen, S. B., Jessen, N. & Møller, N. (2021).
Oral 3-hydroxybutyrate ingestion decreases endogenous glucose production, lipolysis, and hormone-sensitive lipase phosphorylation in adipose tissue in men: a human randomized, controlled, crossover trial.
Diabetic Medicine,
38(2), Article e14385.
https://doi.org/10.1111/dme.14385
Breining, P., Pedersen, S. B., Kjolby, M., Hansen, J. B.
, Jessen, N. & Richelsen, B. (2021).
Parathyroid hormone receptor stimulation induces human adipocyte lipolysis and browning.
European Journal of Endocrinology,
184(5), 687-697.
https://doi.org/10.1530/EJE-20-0713
Olesen, A. E.
, Henriksen, J. N., Nielsen, L. P., Knudsen, P. & Poulsen, B. K. (2021).
Patient safety incidents involving transdermal opioids: data from the Danish Patient Safety Database.
International Journal of Clinical Pharmacy,
43(2), 351-357.
https://doi.org/10.1007/s11096-020-01057-6Kusuyama, J., Alves-Wagner, A. B., Conlin, R. H., Makarewicz, N. S., Albertson, B. G., Prince, N. B., Kobayashi, S., Kozuka, C.
, Møller, M., Bjerre, M., Fuglsang, J., Miele, E., Middelbeek, R. J. W., Xiudong, Y., Xia, Y., Garneau, L., Bhattacharjee, J., Aguer, C., Patti, M. E. ... Goodyear, L. J. (2021).
Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health.
Cell Metabolism,
33(5), 939-956.e8.
https://doi.org/10.1016/j.cmet.2021.03.004Hesse, M., Thomsen, K. R., Thylstrup, B., Andersen, C. U., Reitzel, L. A., Worm-Leonhard, M.
& Lindholst, C. (2021).
Purity of street-level cocaine across Denmark from 2006 to 2019: Analysis of seized cocaine.
Forensic Science International,
329, Article 111050.
https://doi.org/10.1016/j.forsciint.2021.111050
Rittig, N., Aagaard, N. K., Villadsen, G. E., Sandahl, T. D., Jessen, N., Grønbaek, H. & George, J. (2021).
Randomised clinical study: acute effects of metformin versus placebo on portal pressure in patients with cirrhosis and portal hypertension.
Alimentary Pharmacology and Therapeutics,
54(3), 320-328.
https://doi.org/10.1111/apt.16460
Xia, Y., Xiao, J.
, Yu, Y., Tseng, W.-L., Lebowitz, E., DeWan, A. T.
, Pedersen, L. H., Olsen, J., Li, J. & Liew, Z. (2021).
Rates of Neuropsychiatric Disorders and Gestational Age at Birth in a Danish Population.
JAMA network open,
4(6), Article e2114913.
https://doi.org/10.1001/jamanetworkopen.2021.14913Funck, K. L., Knudsen, J. S., Hansen, T. K., Thomsen, R. W. & Grove, E. L. (2021).
Real-world use of cardioprotective glucose-lowering drugs in patients with type 2 diabetes and cardiovascular disease: A Danish nationwide cohort study, 2012 to 2019.
Diabetes, Obesity and Metabolism,
23(2), 520-529.
https://doi.org/10.1111/dom.14245