Department of Biomedicine Research Publications Publications 2025

Publications 2025

Publications 2025

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Janukonyte, J., Parkner, T., Lauritzen, T., Christiansen, J. S., Frystyk, J., Pedersen, H. S. & Laursen, T. (2014). Impact of moderate interval exercise versus supine rest on the pharmacokinetics and pharmacodynamic profiles of subcutaneously administered growth hormone in adult growth hormone deficient patients. Growth Hormone & IGF Research, 24(5), 198-204. https://doi.org/10.1016/j.ghir.2014.06.002
Nellemann, B., Søndergaard, E., Jensen, J., Pedersen, S. B., Jessen, N., Jørgensen, J. O. L. & Nielsen, S. (2014). Kinetics and utilization of lipid sources during acute exercise and acipimox. A J P: Endocrinology and Metabolism (Online), 307(2), E199-208. https://doi.org/10.1152/ajpendo.00043.2014
Laursen, T. & Christiansen, J. S. (2014). Midler ved sygdomme i hypothalamus og hypofysebinyrebarkstereoider og androgener. In K. Brøsen, U. Simonsen, J. P. Kampmann & S. Thirstrup (Eds.), Basal og klinisk farmakologi (5 ed., pp. 420-435). FADL's Forlag.
Laursen, T. & Christiansen, J. S. (2014). Midler ved sygdomme i hypothalamus og hypofyse - binyrebarksteroider og androgener. In K. Brøsen, U. Simonsen, J. P. Kampmann & S. Thirstrup (Eds.), Basal og klinisk farmakologi (5 ed., pp. 420-435). FADL's Forlag.
Bendstrup, E., Hyldgaard, C., Agerbæk, M., Andersen, C. U. & Hilberg, O. (2014). No effect of pirfenidone treatment in fulminant bleomycin-induced pneumonitis. Respiratory Medicine Case Reports, 12, 47-9. https://doi.org/10.1016/j.rmcr.2013.12.010
Jakobsen, S., Busk, M., Munk, O. L., Alstrup, A. K. O., Gormsen, L. C., Jessen, N. & Frøkiær, J. (2014). Preclinical validation of 11C-Metformin: A novel PET tracer targeting organic cation transporters. Abstract from 61th Society of Nuclear Medicine Annual Meeting, Saint Louis, United States.
Ma, Z., Christiansen, J. S., Laursen, T., Lauritzen, T. & Frystyk, J. (2014). Short-term effects of NPH insulin, insulin detemir, and insulin glargine on the GH-IGF1-IGFBP axis in patients with type 1 diabetes. European Journal of Endocrinology, 171(4), 471-9. https://doi.org/10.1530/EJE-14-0258
Poulsen, M. M., Ornstrup, M. J., Harsløf, T., Jessen, N., Langdahl, B. L., Richelsen, B., Jørgensen, J. O. L. & Pedersen, S. B. (2014). Short-term resveratrol supplementation stimulates serum levels of bone-specific alkaline phosphatase in obese non-diabetic men. Journal of Functional Foods, 6, 305. Article http://dx.doi.org/10.1016/j.jff.2013.10.019. https://doi.org/10.1016/j.jff.2013.10.019
Glerup, S., Olsen, D., Vægter, C. B., Gustafsen, C., Sjøgaard, S., Hermey, G., Kjølby, M. F., Jensen, S. M., Ulrichsen, M., Hansen, S. B., Skeldal, S., Fjorback, A. N., Nyengaard, J. R., Jacobsen, J., Bender, D., Bjarkam, C. R., Sørensen, E. S., Füchtbauer, E.-M., Eichele, G. ... Nykjær, A. (2014). SorCS2 Regulates Dopaminergic Wiring and Is Processed into an Apoptotic Two-Chain Receptor in Peripheral Glia. Neuron, 82(5), 1074–1087. https://doi.org/10.1016/j.neuron.2014.04.022
Andersen, C. U., Høimark, L., Dabrowski, K., Hansen, K. B. & Sædder, E. (2014). Sparsom evidens for antipsykotika til behandling af organisk delirium. Ugeskrift for Læger, 176(20), 1858-1862. Article V11130658. https://ugeskriftet.dk/videnskab/sparsom-evidens-antipsykotika-til-behandling-af-organisk-delirium
Sneider, K., Poulsen, M. Ø., Ottosen, C. & Langhoff-Roos, J. (2014). Successful delivery after vaginal occlusion in addition to cerclage in a trachelectomy patient with recurrent second trimester pregnancy loss: a case report. Clinical Case Reports, 2(4), 153-155. https://doi.org/10.1002/ccr3.84
Sneider, K., Poulsen, M. Ø. & Langhoff-Roos, J. (2014). Successful delivery after vaginal occlusion in addition to cerclage in a trachelectomy patient with recurrent second trimester pregnancy losses. Abstract from NFOG, Bergen, Norway. http://www.nfog.org/files/NFOG%202014%20Abstract%20e-book.pdf
Vendelbo, M., Møller, A. B., Treebak, J. T., Gormsen, L. C., Goodyear, L. J., Wojtaszewski, J. F. P., Jørgensen, J. O. L., Møller, N. & Jessen, N. (2014). Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 minutes after a single bout of exercise. Journal of Applied Physiology, 117(3), 289-296. https://doi.org/10.1152/japplphysiol.00044.2014
Mortensen, M. B., Kjolby, M., Gunnersen, S., Larsen, J. V., Palmfeldt, J., Falk, E., Nykjaer, A. & Bentzon, J. F. (2014). Targeting sortilin in immune cells reduces proinflammatory cytokines and atherosclerosis. Journal of Clinical Investigation, 124(12), 5317-5322. https://doi.org/10.1172/JCI76002
Gustafsen, C., Kjolby, M., Nyegaard, M., Mattheisen, M., Lundhede, J., Buttenschøn, H., Mors, O., Bentzon, J. F., Madsen, P., Nykjaer, A. & Glerup, S. (2014). The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion. Cell Metabolism, 19(2), 310-8. https://doi.org/10.1016/j.cmet.2013.12.006
Hyldgaard, C., Bendstrup, E., Leth, S., Andersen, C. U. & Hilberg, O. (2013). A Simple HRCT Staging System in Idiopathic Fibrotic Interstitial Lung Disease. American Journal of Respiratory and Critical Care Medicine, 187.
Hangaard, J., Andersen, M., Laursen, T., Nielsen, E. H., Storm, T. L., Rasmussen, Å. K., Poulsen, P. L., Friberg, A., Ladekarl, M., Schaffalitzky de Muckadell, O. B., Wilson, B., Knigge, U. P. & Grønbæk, H. (2013). Baggrundsnotat for brug af langtidsvirkende somatostatinanaloger og GH-receptorantagonist til akromegali. In Baggrundsnotat for brug af langtidsvirkende somatostatinanaloger og GH-receptorantagonist til akromegali. http://www.regioner.dk/~/media/Mediebibliotek_2011/SUNDHED/Medicin/Rådet%20for%20Anvendelse%20af%20Dyr%20Sygehusmedicin/20121221%20Baggrundsnotat_akromegali%20godkendt%20af%20RADS.ashx
Knigge, U. P., Grønbæk, H., Ladekarl, M., Schaffalitzky de Muckadell, O. B., Wilson, B., Hangaard, J., Andersen, M., Laursen, T., Friberg, A., Nielsen, E. H., Storm, T. L., Rasmussen, Å. K. & Poulsen, P. L. (2013). Baggrundsnotat for brug af langtidsvirkende somatostatinanaloger til neuroendokrine tumorer. In Baggrundsnotat for brug af langtidsvirkende somatostatinanaloger til neuroendokrine tumorer http://www.regioner.dk/~/media/Mediebibliotek_2011/SUNDHED/Medicin/R%E5det%20for%20Anvendelse%20af%20Dyr%20Sygehusmedicin/020513%20Baggrundsnotat%20for%20brug%20af%20langtidsvirkende%20somatostatinanaloger%20til%20neuroendokrine%20tumorer.ashx
Janukonyte, J., Parkner, T., Lauritzen, T., Christiansen, J. S. & Laursen, T. (2013). Circadian variation in the pharmacokinetics of steady state continuous subcutaneous infusion of growth hormone in adult growth hormone deficient patients. Growth Hormone & IGF Research, 23(6), 256-260. https://doi.org/10.1016/j.ghir.2013.09.002
Vissing, K., McGee, S. L., Farup, J., Kjølhede, T., Vendelbo, M. H. & Jessen, N. (2013). Differentiated mTOR but not AMPK signaling after strength vs endurance exercise in training-accustomed individuals. Scandinavian Journal of Medicine & Science in Sports, 23(3), 355-66. https://doi.org/10.1111/j.1600-0838.2011.01395.x
Buhl, M., Bosnjak, E., Vendelbo, M. H., Gjedsted, J., Nielsen, B. R. R., Hafstrøm, T. K., Vestergaard, E. T., Jessen, N., Tønnesen, E., Møller, A. B., Pedersen, S. B., Pilegaard, H., Biensø, R. S., Jørgensen, J. O. L. & Møller, N. (2013). Direct effects of locally administered lipopolysaccharide on glucose, lipid, and protein metabolism in the placebo-controlled, bilaterally infused human leg. Journal of Clinical Endocrinology and Metabolism, 98(5), 2090-9. https://doi.org/10.1210/jc.2012-3836
Bach, E., Nielsen, B. R. R., Vendelbo, M. H., Møller, A. B., Jessen, N., Buhl, M., Hafstrøm, T. K., Holm, L., Pedersen, S. B., Pilegaard, H., Biensø, R. S., Jørgensen, J. O. L. & Møller, N. (2013). Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo controlled bilaterally infused human leg; increased insulin sensitivity, increased net protein breakdown and increased IL-6 release. Diabetes. https://doi.org/10.2337/db13-0138
Clasen, B. F. F., Hafstrøm, T. K., Vendelbo, M. H., Thorsen, K., Escande, C., Moller, N., Pedersen, S. B., Jørgensen, J. O. L. & Jessen, N. (2013). Gene Expression in Skeletal Muscle after an Acute Intravenous GH Bolus in Human Subjects: Identification of a Mechanism Regulating ANGPTL4. Journal of Lipid Research, 54(7), 1988-1997. https://doi.org/10.1194/jlr.P034520
Vestergaard, E. T., Krag, M. B., Poulsen, M. M., Pedersen, S. B., Moller, N., Jorgensen, J. O. L. & Jessen, N. (2013). Ghrelin- and GH-induced insulin resistance: no association with retinol-binding protein-4. Endocrine Connections, 2(2), 96-103. https://doi.org/10.1530/EC-13-0019
Poulsen, M. M., Vestergaard, P. F., Clasen, B. F., Radko, Y., Christensen, L. P., Stødkilde-Jørgensen, H., Møller, N., Jessen, N., Pedersen, S. B. & Jørgensen, J. O. L. (2013). High-Dose Resveratrol Supplementation in Obese Men: An Investigator-Initiated, Randomized, Placebo-Controlled Clinical Trial of Substrate Metabolism, Insulin Sensitivity, and Body Composition. Diabetes, 62 (4), 1186-1195. https://doi.org/10.2337/db12-0975
Carlsen, T. G., Hjelholt, A. J., Jurik, A. G., Schiøttz-Christensen, B., Zejden, A., Christiansen, G., Deleuran, B. & Birkelund, S. (2013). IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis. Arthritis research & therapy, 15(3), R61. https://doi.org/10.1186/ar4234
Nielsen, A. H., Christiansen, G., Sørensen, U. B. S. & Birkelund, S. (2013). IgG subclass profiles in normal human sera of antibodies specific to five kinds of microbial antigens. Pathogens and Disease, 67, 206-213. https://doi.org/10.1111/2049-632X.12034
Nielsen, A. H., Carlsen, T., Deleuran, B., Jurik, A. G., Schiøttz-Christensen, B., Christiansen, G. & Birkelund, S. (2013). Increased Levels of IgG Antibodies against Human HSP60 in Patients with Spondyloarthritis. PLoS One, 8(2), e56210. https://doi.org/10.1371/journal.pone.0056210
Høst, C., Gormsen, L. C., Christensen, B., Jessen, N., Hougaard, D. M., Christiansen, J. S., Pedersen, S. B., Jensen, M. D. & Gravholt, C. H. (2013). Independent Effects of Testosterone on Lipid Oxidation and VLDL-TG Production: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study. Diabetes, 62(5), 1409-16. https://doi.org/10.2337/db12-0440
Jeppesen, J. F., Maarbjerg, S. J., Jordy, A. B., Fritzen, A. M., Pehmøller, C. K., Hansen, L. S., Serup, A. K. L., Jessen, N., Thorsen, K., Prats, C., Qvortrup, K., Dyck, J. R. B., Hunter, R. W., Sakamoto, K., Thomson, D. M., Schjerling, P., Wojtaszewski, J., Richter, E. & Kiens, B. (2013). LKB1 regulates lipid oxidation during exercise independently of AMPK. Diabetes, 62(5), 1490-9. https://doi.org/10.2337/db12-1160
Bonnerup, D. K., Lisby, M., Eskildsen, A. G., Sædder, E. & Nielsen, L. P. (2013). Medication Counselling: Physicians' Perspective. Basic & Clinical Pharmacology & Toxicology. https://doi.org/10.1111/bcpt.12111
Keller, A. K., Lassen, C. K., Møldrup, U., Bibby, B. M. & Jespersen, B. (2013). Messengers of renal graft quality during warm and cold ischemia - a porcine microdialysis study. Transplantation Proceedings, 45(3), 1172-7.
Etzerodt, A., Kjolby, M., Nielsen, M. J., Maniecki, M. B., Svendsen, P. & Moestrup, S. K. (2013). Plasma clearance of hemoglobin and haptoglobin in mice and effect of CD163 gene targeting disruption. Antioxidants & Redox Signaling, 18(17), 2254-2263. https://doi.org/10.1089/ars.2012.4605
Laursen, R. V., Hansen, S. B., Risager, M. B. & Omland, Ø. (2013). Prævalensen af methicillinresistente Staphylococcus aureus er stigende i dansk landbrug. Ugeskrift for Læger, 2-5.
Andersen, C. U., Sønderskov, L. D., Nielsen-Kudsk, J. E., Simonsen, U., Bendstrup, E., Hilberg, O. & Mellemkjær, S. (2013). [Pulmonary hypertension--classification, work-up and treatment]. Ugeskrift for Læger, 175(23), 1642-1645.
Andersen, C. U., Mellemkjær, S., Nielsen-Kudsk, J. E., Bendstrup, E., Hilberg, O. & Simonsen, U. (2013). Pulmonary hypertension in chronic obstructive and interstitial lung diseases. International Journal of Cardiology, 168(3), 1795-1804. https://doi.org/10.1016/j.ijcard.2013.06.033
Thomsen, K. L., Jessen, N., Buch Møller, A., Aagaard, N. K., Grønbæk, H., Holst, J. J. & Vilstrup, H. (2013). Regulation of urea synthesis during the acute phase response in rats. American Journal of Physiology: Gastrointestinal and Liver Physiology, 304(7), G680-6. https://doi.org/10.1152/ajpgi.00416.2012
Poulsen, M. M., Jørgensen, J. O. L., Jessen, N., Richelsen, B. & Pedersen, S. B. (2013). Resveratrol in metabolic health: an overview of the current evidence and perspectives. New York Academy of Sciences. Annals, 1290(1), 74-82. https://doi.org/10.1111/nyas.12141
Poulsen, M. M., Ornstrup, M. J., Harsløf, T., Jessen, N., Langdahl, B. L., Richelsen, B., Jørgensen, J. O. L. & Pedersen, S. B. (2013). Short-term resveratrol supplementation stimulates serum levels of bone-specific alkaline phosphatase in obese non-diabetic men. Poster session presented at ECTS meeting, Lisbon, Portugal.
Glerup, S., Lume, M., Olsen, D., Nyengaard, J. R., Vaegter, C. B., Gustafsen, C., Christensen, E. I., Kjolby, M., Hay-Schmidt, A., Bender, D., Madsen, P., Saarma, M., Nykjaer, A. & Petersen, C. M. (2013). SorLA Controls Neurotrophic Activity by Sorting of GDNF and Its Receptors GFRα1 and RET. Cell Reports, 3, 186-199. https://doi.org/10.1016/j.celrep.2012.12.011
Soerensen, A. L., Lisby, M., Nielsen, L. P., Poulsen, B. K. & Mainz, J. (2013). The medication process in a psychiatric hospital: are errors a potential threat to patient safety? Risk Management and Healthcare Policy, 6, 23-31. https://doi.org/10.2147/RMHP.S47723
Christensen, B., Nellemann, B., Larsen, M. S., Thams, L., Sieljacks, P., Vestergaard, P. F., Bibby, B. M., Vissing, K., Stødkilde-Jørgensen, H., Pedersen, S. B., Møller, N., Nielsen, S., Jessen, N. & Jørgensen, J. O. L. (2013). Whole body metabolic effects of prolonged endurance training in combination with erythropoietin treatment in humans: a randomized placebo controlled study. A J P: Endocrinology and Metabolism (Online), 305(7), E879-889. https://doi.org/10.1152/ajpendo.00269.2013
Ma, Z., Parkner, T., Frystyk, J., Laursen, T., Lauritzen, T. & Christiansen, J. S. (2012). A comparison of pharmacokinetics and pharmacodynamics of insulin aspart, biphasic insulin aspart 70, biphasic insulin aspart 50, and human insulin: a randomized, quadruple crossover study. Diabetes Technology & Therapeutics, 14(7), 589-95. https://doi.org/10.1089/dia.2011.0299
Vissing, K., McGee, S. L., Farup, J., Kjølhede, T., Vendelbo, M. H. & Jessen, N. (2012). AMPK vs mTORC1 signaling: genuine exercise effects of differentiated exercise in humans: Response to letter to editor by Dr A. K. Yamada. Scandinavian Journal of Medicine & Science in Sports, 22(4), 580-1. https://doi.org/10.1111/j.1600-0838.2012.01450.x
Thomsen, K. L., Sandahl, T. D., Holland-Fischer, P., Jessen, N., Frystyk, J., Flyvbjerg, A., Grønbæk, H. & Vilstrup, H. (2012). Changes in adipokines after transjugular intrahepatic porto-systemic shunt indicate an anabolic shift in metabolism. Clinical Nutrition. https://doi.org/10.1016/j.clnu.2012.04.001
Andersen, C. U., Mellemkjær, S., Nielsen-Kudsk, J. E., Bendstrup, E., Simonsen, U. & Hilberg, O. (2012). Diagnostic and prognostic role of biomarkers for pulmonary hypertension in interstitial lung disease. Respiratory Medicine. https://doi.org/10.1016/j.rmed.2012.09.003
Buhl, M., Bosnjak, E., Gjedsted, J., Nielsen, B. R. R., Jessen, N., Hafstrøm, T. K., Vestergaard, E. T., Tønnesen, E. K. & Møller, N. (2012). Direct metabolic effects of locally administered lipopolysaccharide in the placebo controlled bilaterally infused human leg; decreased insulin sensitivity and insulin signaling with unaltered lipid and protein metabolism. Abstract from ICE/ECE 2012, Florence, Italy. http://www.endocrine-abstracts.org/ea/0029/ea0029p533.htm
Buhl, M., Bosnjak, E., Gjedsted, J., Nielsen, B. R. R., Jessen, N., Hafstrøm, T. K., Vestergaard, E. T., Tønnesen, E. K. & Møller, N. (2012). Direct metabolic effects of locally administered lipopolysaccharide in the placebo controlled bilaterally infused human leg; decreased insulin sensitivity and insulin signaling with unaltered lipid and protein metabolism. Poster session presented at ICE/ECE 2012, Florence, Italy. http://www.endocrine-abstracts.org/ea/0029/ea0029p533.htm
Andersen, C. U., Mellemkjær, S., Nielsen-Kudsk, J. E., Sønderskov, L. D., Laursen, B. E., Simonsen, U. & Hilberg, O. (2012). Echocardiographic screening for pulmonary hypertension in stable COPD out-patients and NT-proBNP as a rule-out test. C O P D, 505. https://doi.org/10.3109/15412555.2012.695818
Christensen, B., Vendelbo, M. H., Hafstrøm, T. K., Madsen, M., Pedersen, S. B., Jessen, N., Møller, N. & Jørgensen, J. O. L. (2012). Erythropoietin administration acutely stimulates resting energy expenditure in healthy young men. Journal of Applied Physiology, 112(7), 1114-21. https://doi.org/10.1152/japplphysiol.01391.2011

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Ellen Kristensen