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Publications 2025

Publications 2025

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Christensen, B., Sackmann-Sala, L., Cruz-Topete, D., Jørgensen, J. O. L., Jessen, N., Lundby, C. & Kopchick, J. J. (2011). Novel serum biomarkers for erythropoietin use in humans: a proteomic approach. Journal of Applied Physiology, 110(1), 149-56. https://doi.org/10.1152/japplphysiol.00665.2010

Münster, A.-M. B. & Poulsen, B. K. (2011). Oplæg til regional instruks vedr. håndtering af specielle situationer ved behandling med Dabigatran (Pradaxa®). DSTH Forum, 2011(5), 8-10.

Søndergaard, E., Klose, M. C., Hansen, M., Hansen, B. S., Andersen, M., Feldt-Rasmussen, U., Laursen, T., Rasmussen, M. H. & Christiansen, J. S. (2011). Pegylated Long-Acting Human Growth Hormone Possesses a Promising Once-Weekly Treatment Profile, and Multiple Dosing Is Well Tolerated in Adult Patients with Growth Hormone Deficiency. Journal of Clinical Endocrinology and Metabolism, 96(3), 681-688. https://doi.org/10.1210/jc.2010-1931

Ihlo, C. A., Lauritzen, T., Sturis, J., Skyggebjerg, O., Christiansen, J. S. & Laursen, T. (2011). Pharmacokinetics and pharmacodynamics of different modes of insulin pump delivery. A randomized, controlled study comparing subcutaneous and intravenous administration of insulin aspart. Diabetic Medicine, 28(2), 230-6. https://doi.org/10.1111/j.1464-5491.2010.03149.x

Nielsen, K. R., Kølbæk, M. D., Høj, K., Baech, J. & Nielsen, B. W. (2011). Primær autoimmun neutropeni hos børn. Ugeskrift for Læger, 173(46), 2954-2957.

Andersen, L., Høimark, L. & Nielsen, L. P. (2011). Respimat mist inhaler safety. B M J (Online). http://www.bmj.com/rapid-response/2011/11/03/respimat-mist-inhaler-safety

Vaegter, C. B., Jansen, P., Fjorback, A. W., Glerup, S., Skeldal, S., Kjølby, M. F., Richner, M., Erdmann, B., Nyengaard, J. R., Tessarollo, L., Lewin, G. R., Willnow, T. E., Chao, M. V. & Nykjaer, A. (2011). Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nature Neuroscience, 14(1), 54-61. https://doi.org/10.1038/nn.2689

Kjølby, M. F. (2011). Sortilins in cardiovascular disease and diabetes. Århus Universitet.

Willnow, T., Kjølby, M. F. & Nykjær, A. (2011). Sortilins: new players in lipoprotein metabolism. Current Opinion in Lipidology, 22(2), 79-85. https://doi.org/10.1097/MOL.0b013e3283416f2b

Kappelgaard, A.-M. & Laursen, T. (2011). The benefits of growth hormone therapy in patients with Turner syndrome, Noonan syndrome and children born small for gestational age. Growth Hormone & IGF Research, 21(6), 305-13. https://doi.org/10.1016/j.ghir.2011.09.004

Gormsen, L. C., Nielsen, C., Jessen, N., Jørgensen, J. O. L. & Møller, N. (2011). Time-course effects of physiological free fatty acid surges on insulin sensitivity in humans. Acta Physiologica (Print), 201(3), 349-356. https://doi.org/10.1111/j.1748-1716.2010.02181.x

Nielsen, A. H., Christiansen, G., Johannesson, T. G., Ingerslev, H. J. & Birkelund, S. (2011). Tubal factor infertility is associated with antibodies against Chlamydia trachomatis heat shock protein 60 (HSP60) but not human HSP60. Human Reproduction, 26(8), 2069-76. https://doi.org/10.1093/humrep/der167

Jessen, N., Koh, H.-J., Folmes, C. D., Wagg, C., Fujii, N., Løfgren, B., Wolf, C. M., Berul, C. I., Hirshman, M. F., Lopaschuk, G. D. & Goodyear, L. J. (2010). Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function. BBA General Subjects, 1802(7-8), 593-600. https://doi.org/10.1016/j.bbadis.2010.04.008

Laursen, T. (2010). Advances in the Understanding of Adult Growth Hormone Deficiency Syndrome - Diagnosis, Epidemiology and Management. European Endocrinology, 6(2), 45-50.

Vissing, K., McGee, S. L., Farup, J., Kjølhede, T., Vendelbo, M. & Jessen, N. (2010). Akt-mTOR signaling is selectively activated by resistance exercise, while AMPK signaling exhibits redundancy between endurance exercise and resistance exercise in training-accustomed individuals.. Poster session presented at European Muscle Conference (EMC), Padova, Italy.

Witczak, C. A., Jessen, N., Warro, D. M., Toyoda, T., Fujii, N., Anderson, M. E., Hirshman, M. F. & Goodyear, L. J. (2010). CaMKII regulates contraction- but not insulin-induced glucose uptake in mouse skeletal muscle. American Journal of Physiology: Endocrinology and Metabolism, 298(6), E1150-60. https://doi.org/10.1152/ajpendo.00659.2009

Vichaiwong, K., Purohit, S., An, D., Toyoda, T., Jessen, N., Xie, J., Hirshman, M. F. & Goodyear, L. J. (2010). Contraction Regulates Site-Specific Phosphorylation of TBC1D1 in Skeletal Muscle. Biochemical Journal, 431(2), 311-20. https://doi.org/10.1042/BJ20101100

Kjølby, M. F. (2010). Det store lotteri. Weekendavisen.

Jessen, N. & Goodyear, L. J. (2010). Diabetes: Exercise and type 2 diabetes mellitus--good for body and mind? Nature Reviews. Endocrinology, 6(6), 303-4. https://doi.org/10.1038/nrendo.2010.47

Vendelbo, M., Jørgensen, J. O., Pedersen, S. B., Gormsen, L. C., Lund, S., Schmitz, O., Jessen, N. & Møller, N. (2010). Exercise and Fasting Activate Growth Hormone-Dependent Myocellular Signal Transducer and Activator of Transcription-5b Phosphorylation and Insulin-Like Growth Factor-I Messenger Ribonucleic Acid Expression in Humans. Journal of Clinical Endocrinology and Metabolism, 95(9), E64-68. https://doi.org/10.1210/jc.2010-0689

Laursen, T. & Kristensen, L. Ø. (2010). Midler ved sygdomme i hypothalamus og hypofyse - binyrebarksteroider og androgener. In J. P. Kampmann, K. Brøsen & U. Simonsen (Eds.), Basal og klinisk farmakologi (4 ed., pp. 373-87). FADL's Forlag.

Parkner, T., Dyrskog, S. E., Laursen, T., Chen, J. W., Mouritzen, U., Brondsted, L., Hermansen, K., Lauritzen, T. & Christiansen, J. S. (2010). Obesity does not influence the unique pharmacological properties of different biphasic insulin aspart preparations in patients with type 2 diabetes. Diabetes, Obesity and Metabolism, 12(5), 414-20. https://doi.org/10.1111/j.1463-1326.2009.01178.x

Petersen, S. B., Kildegaard, J., Nielsen, F. S., Søndergaard, E., Parkner, T., Laursen, T., Lauritzen, T., Skyggebjerg, O. & Christiansen, J. S. (2010). Pharmacokinetics following continuous subcutaneous insulin infusion of insulin aspart with or without initial subcutaneous bolus. Diabetes, Obesity and Metabolism, 12(4), 334-40. https://doi.org/10.1111/j.1463-1326.2009.01168.x

Bennetzen, M. F., Nielsen, T. S., Paulsen, S. K., Bendix, J., Fisker, S., Jessen, N., Lund, S., Richelsen, B. & Pedersen, S. B. (2010). Reduced cannabinoid receptor 1 protein in subcutaneous adipose tissue of obese. European Journal of Clinical Investigation, 40(2), 121-126. https://doi.org/10.1111/j.1365-2362.2009.02231.x

Kjølby, M. F., Andersen, O. M., Breiderhoff, T., Fjorback, A. N., Pedersen, K.-M., Madsen, P. S., Jansen, P., Heeren, J., Willnow, T. & Nykjær, A. (2010). Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export. Cell Metabolism, 12(3), 213-223.

Buhl, E. S., Jensen, T. K., Jessen, N., Elfving, B., Buhl, C. S., Kristiansen, S. B., Pold, R., Solskov, L., Schmitz, O., Wegener, G., Lund, S. & Petersen, K. F. (2010). TREATMENT WITH AN SSRI ANTIDEPRESSANT RESTORES HIPPOCAMPO-HYPOTHALAMIC CORTICOSTEROID FEEDBACK AND REVERSES INSULIN RESISTANCE IN LOW BIRTH WEIGHT RATS. American Journal of Physiology: Endocrinology and Metabolism, 298(5), E920-9. https://doi.org/10.1152/ajpendo.00606.2009

Thomsen, K. L., Aagaard, N. K., Nielsen, S. S., Grønbæk, H., Jessen, N., Frystyk, J. & Vilstrup, H. (2010). Unchanged capacity of urea synthesis during acute phase response in rats. European Journal of Clinical Investigation, 41(1), 16-22. https://doi.org/10.1111/j.1365-2362.2010.02369.x

Kristiansen, S. B., Solskov, L., Jessen, N., Løfgren, B., Schmitz, O., Nielsen-Kudsk, J. E., Nielsen, T. T., Bøtker, H. E. & Lund, S. (2009). 5-Aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside Increases Myocardial Glucose Uptake during Reperfusion and Induces Late Pre-conditioning: Potential Role of AMP-Activated Protein Kinase. Basic & Clinical Pharmacology & Toxicology, 105(1), 10-16. https://doi.org/10.1111/j.1742-7843.2009.00402.x

Gollisch, K. S. C., Brandauer, J., Jessen, N., Toyoda, T., Nayer, A., Hirshman, M. F. & Goodyear, L. J. (2009). Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats. American Journal of Physiology: Endocrinology and Metabolism, 297(2), E495-504. https://doi.org/10.1152/ajpendo.90424.2008

Møller, N., Gormsen, L. C., Schmitz, O., Lund, S., Jørgensen, J. O. L. & Jessen, N. (2009). Free fatty acids inhibit growth hormone/signal transducer and activator or transcription-5 in signaling in human muscle: a potential feedback mechanism. Journal of Clinical Endocrinology and Metabolism, 94, 2204-2207. https://doi.org/10.1210/jc.2008-2624

Møller, L., Nørrelund, H., Jessen, N., Flyvbjerg, A., Pedersen, S. B., Gaylinn, B. D., Liu, J., Thorner, M. O., Møller, N. & Jørgensen, J. O. L. (2009). Impact of Growth Hormone Receptor Blockade on Substrate Metabolism during Fasting in Healthy Subjects. Journal of Clinical Endocrinology and Metabolism, 94(11), 4524-4532. https://doi.org/10.1210/jc.2009-0381

Laursen, T. (2009). Kommende læger mangler viden om lægemidler: Nogle yngre læger har en dyb uvidenhed om lægemidler, fordi undervisning i farmakologi ikke har fyldt nok i deres studie. Pharma, 20-23.

Vestergaard, E. T., Buhl, M., Gjedsted, J., Madsen, M., Jessen, N., Jørgensen, J. O. L. & Møller, N. (2009). Peripheral metabolic effects of intra-arterial ghrelin infusion in healthy young men: . Poster session presented at The Endocrine Society's 91st Annual Meeting, Washington, United States.

Andersen, C. U., Markvardsen, L. H., Hilberg, O. & Simonsen, U. (2009). Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension. Respiratory Medicine, 103(11), 1663-71. https://doi.org/10.1016/j.rmed.2009.05.011

Ihlo, C. A., Aksglæde, K., Laursen, T., Lauritzen, T. & Christiansen, J. S. (2009). Serum insulin aspart concentrations following high-dose insulin aspart administered directly into the duodenum of healthy subjects: An open-labeled, single-blinded and uncontrolled exploratory trial. Journal of Diabetes Science and Technology, 3(5), 1183-91.

Smidt, K., Jessen, N., Petersen, A. B., Larsen, A., Magnusson, N., Jeppesen, J. B., Stoltenberg, M., Culvenor, J. G., Tsatsanis, A., Brock, B., Schmitz, O., Wogensen, L., Bush, A. I. & Rungby, J. (2009). SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress. P L o S One, 4(5), e5684. https://doi.org/10.1371/journal.pone.0005684

Nykjær, A. & Kjølby, M. F. (2009). (WO/2009/140972) MODULATION OF THE VPS10P-DOMAIN RECEPTORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE. (Patent No. PCT/DK2009/050115).

Fujii, N., Ho, R. C., Manabe, Y., Jessen, N., Toyoda, T., Holland, W. L., Summers, S. A., Hirshman, M. F. & Goodyear, L. J. (2008). Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice. Diabetes, 57(11), 2958-66. https://doi.org/10.2337/db07-1187

Jessen, N., Selmer Buhl, E., Pold, R., Schmitz, O. & Lund, S. (2008). A novel insulin sensitizer (S15511) enhances insulin-stimulated glucose uptake in rat skeletal muscles. Hormone and Metabolic Research, 40(4), 269-75. https://doi.org/10.1055/s-2007-1022546

Kress, H. G., Von der Laage, D., Hoerauf, K. H., Nolte, T., Heiskanen, T., Petersen, R., Lundorff, L., Sabatowski, R., Krenn, H., Rosland, J. H., Saedder, E. A. & Jensen, N.-H. (2008). A randomized, open, parallel group, multicenter trial to investigate analgesic efficacy and safety of a new transdermal fentanyl patch compared to standard opioid treatment in cancer pain. Journal of Pain and Symptom Management, 36(3), 268-79. https://doi.org/10.1016/j.jpainsymman.2007.10.023

Kjølby, M. F. & Bie, P. (2008). Chronic activation of plasma renin is log-linearly related to dietary sodium and eliminates natriuresis in response to a pulse change in total body sodium. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 294(1), r17-25.

Norris, A. W., Hirshman, M. F., Yao, J., Jessen, N., Musi, N., Chen, L., Sivitz, W. I., Goodyear, L. J. & Kahn, C. R. (2008). Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle. Endocrinology, 149(11), 5374-83. https://doi.org/10.1210/en.2008-0100

Vestergaard, E. T., Gormsen, L. C., Jessen, N., Lund, S., Hansen, T. K., Møller, N. & Jørgensen, J. O. L. (2008). Ghrelin infusion in humans induces acute insulin resistance and lipolysis independent of growth hormone signaling. Diabetes, 57(12), 3205-10. https://doi.org/10.2337/db08-0025

Bro-Jeppesen, J., Larsen, A., Jessen, N., Magnusson, N., Egefjord, L., Wogensen, L., B., B., Schmitz, O., K., S., Stoltenberg, M. & J., R. (2008). Glucose and zinc-depletion stimulate beta cell expression of ZnT3, a zinc transporter, whereas ZnT3 KO mice have decreased beta cell capacity. Diabetologia, 50(Suppl. 1), S207.

Nielsen, C., Gormsen, L. C., Jessen, N., Pedersen, S. B., Møller, N., Lund, S. & Jørgensen, J. O. L. (2008). Growth hormone signaling in vivo in human muscle and adipose tissue: impact of insulin, substrate background, and growth hormone receptor blockade. Journal of Clinical Endocrinology and Metabolism, 93(7), 2842-50. https://doi.org/10.1210/jc.2007-2414

Parkner, T., Laursen, T., Vestergaard, E. T., Hartvig, H., Smedegaard, J. S., Lauritzen, T. & Christiansen, J. S. (2008). Insulin and glucose profiles during continuous subcutaneous insulin infusion compared with injection of a long-acting insulin in Type 2 diabetes. Diabetic Medicine, 25(5), 585-91. https://doi.org/10.1111/j.1464-5491.2008.02418.x

Solskov, L., Løfgren, B., Kristiansen, S. B., Jessen, N., Pold, R., Nielsen, T. T., Bøtker, H. E., Schmitz, O. & Lund, S. (2008). Metformin induces cardioprotection against ischaemia/reperfusion injury in the rat heart 24 hours after administration. Basic & Clinical Pharmacology & Toxicology, 103(1), 82-7. https://doi.org/10.1111/j.1742-7843.2008.00234.x

Stochholm, K., Laursen, T., Green, A., Laurberg, P., Andersen, M., Kristensen, L. Ø., Feldt-Rasmussen, U., Christiansen, J. S., Frydenberg, M. & Gravholt, C. H. (2008). Morbidity and GH deficiency: a nationwide study. European Journal of Endocrinology, 158(4), 447-57. https://doi.org/10.1530/EJE-07-0523

Parkner, T., Møller, M. K., Chen, J.-W., Laursen, T., Jørgensen, C., Smedegaard, J. S., Lauritzen, T. & Christiansen, J. S. (2008). Overnight CSII as supplement to oral antidiabetic drugs in type 2 diabetes. Diabetes, Obesity and Metabolism, 10(7), 556-63. https://doi.org/10.1111/j.1463-1326.2007.00748.x

Petersen, A. H., Kohler, G., Korsatko, S., Wutte, A., Wonisch, M., Mautner, A., Rønn, B. B., Clauson, P., Laursen, T., Wollmer, P. & Pieber, T. R. (2008). The effect of exercise on the absorption of inhaled human insulin in healthy volunteers. British Journal of Clinical Pharmacology, 65(2), 165-171.

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Ellen Kristensen